SILMA
Silk Methacryloyl
Catalogue Number : TI/SILMA/30
Minimum Order Quantity : 15G
Silk Source : Bombyx Mori
Degree of Substitution : 20-30%
Form : Powder
Appearance : Off-White
Recommended Photo-initiator : LAP
About SILMA :
Silk Fibroin Methacryloyl, or SILMA, is an innovative biomaterial derived from natural silk fibroin proteins with added methacryloyl groups. Known for its remarkable mechanical strength, biocompatibility, and biodegradability, SILMA is increasingly used in tissue engineering and bioprinting. This material provides a robust, yet flexible scaffold that supports cell attachment and proliferation, making it suitable for creating complex, load-bearing tissue constructs, such as bone, cartilage, and tendon models.
SILMA’s UV-crosslinking capability allows for precise control over the hydrogel’s physical properties, enabling tailored solutions for various applications. By combining the unique properties of silk fibroin with the versatility of methacrylate chemistry, SILMA offers enhanced structural integrity and a biomimetic environment, contributing significantly to advancements in regenerative medicine and customized bioprinting technologies.
Key Features of SILMA :
01
Photocrosslinkable and Tunable Stiffness ensuring controlled gelation
02
Superior Biocompatibility for Cell Adhesion and Proliferation
03
Enhanced Mechanical Strength for Load Bearing Applications
04
Diverse Applications : Compatible with Bioprinting, Injectables and Cell Culture
Applications of SILMA :
Bioprinting of Soft Tissues
Studies have shown that SILMA-based hydrogels promote angiogenesis, making them promising scaffolds for vascular tissue regeneration and wound healing research. When combined with other biomaterials such as GelMA (gelatin methacryloyl), SILMA forms composite hydrogels with enhanced mechanical strength and biocompatibility, suitable for soft tissue and vascular tissue engineering
Tissue Engineering
SILMA is an advanced, photocrosslinkable biomaterial engineered for tissue engineering research, offering tunable mechanical properties, high biocompatibility, and a porous structure ideal for supporting cell growth, drug delivery, and regeneration in neural, cartilage, and osteochondral tissue models. LINK
Wound Healing
SILMA (Silk Methacryloyl) hydrogels are ideal for wound healing research, offering a biocompatible, porous scaffold that accelerates tissue regeneration, promotes angiogenesis, and supports controlled release of therapeutic agents for enhanced and rapid wound repair. LINK
Controlled Drug Delivery
SILMA enables the development of advanced drug delivery systems for research, offering biocompatible, tunable hydrogels that support sustained and controlled release of therapeutic agents, making it ideal for targeted and sequential drug delivery applications. LINK
Fundamental Cell Research
SILMA hydrogels provide an ideal 3D microenvironment for cellular interaction studies, offering tunable mechanical properties, excellent biocompatibility, and enhanced cell adhesion—making them highly effective for investigating cell behavior, differentiation, and tissue regeneration in advanced research applications LINK
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PVA-MA
Polyvinyl Alcohol Methacryloyl
Synthetic Polymer
Degree of Substitution : 30%
Form : Powder
Appearance : Off-White to White
Recommended Photo-initiator : LAP
GELMA
Gelatin Methacryloyl
300G Bloom Strength (Type A Gelatin) | Porcine
Degree of Substitution : 80%
Form : Powder
Appearance : Off-White
Recommended Photo-initiator : LAP
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